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Are psychiatric biomarkers advanced enough to supplant it? Growing points: The need for biomarkers of psychiatric disorders has become more acute with the advent of new treatments which require precision and an individualized approach. Areas of controversy: The cross-sectional and longitudinal observation of psychopathology is the bedrock of current clinical practice. Areas of agreement: Availability of clinically useful biomarkers will improve the prognosis and outcome of psychiatric patients by helping in early diagnosis and delivery of individualized treatment. Sources of data: The data quoted in this paper are gathered from a range of sources encompassing scientific and journalistic both in print and electronic.

In clinical practice, it undermines the validity of psychiatric diagnoses and hampers the delivery of personalized treatment.

Introduction: The dearth of biomarkers limits the precision of our research into pathogenesis of psychiatric disorders and has slowed down the development of new drugs.

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